Structure of PDB 1x2h Chain A

Receptor sequence
>1x2hA (length=330) Species: 562 (Escherichia coli) [Search protein sequence]
STLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQN
PWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTIS
TSIVLNALNALGVSAEASGRNDLVVKTVEGDRKVSGSAYRETKDRGFHHG
TLLLNADLSRLANYLNPDKKKLAAKRVTNLTELLPGITHEQVCEAITEAF
FAHYGERVEAEIISPNKTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDE
RFTWGGVELHFDVEKGHITRAQVFTDSLNPAPLEALAGRLQGCLYRADML
QQECEALLVDFPEQEKELRELSAWMAGAVR
3D structure
PDB1x2h Crystal structure of lipoate-protein ligase A from Escherichia coli: Determination of the lipoic acid-binding site
ChainA
Resolution2.91 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.1.20: lipoate--protein ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LPA A E21 F24 S72 F147 H149 E21 F24 S72 F147 H149
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0016979 lipoate-protein ligase activity
GO:0017118 lipoyltransferase activity
Biological Process
GO:0009249 protein lipoylation
GO:0036211 protein modification process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1x2h, PDBe:1x2h, PDBj:1x2h
PDBsum1x2h
PubMed16043486
UniProtP32099|LPLA_ECOLI Lipoate-protein ligase A (Gene Name=lplA)

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