Structure of PDB 1x1s Chain A

Receptor sequence
>1x1sA (length=163) Species: 10090 (Mus musculus) [Search protein sequence]
LPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQW
AILDVLDTFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKD
RESFPMILVANKVDLMHLRKVTRDQGKEMATKYNIPYIETSAKDPPLNVD
KTFHDLVRVIRQQ
3D structure
PDB1x1s Crystal Structure of M-Ras Reveals a GTP-bound "Off" State Conformation of Ras Family Small GTPases
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP A G23 G25 K26 S27 A28 F38 D41 N126 K127 D129 L130 S156 G13 G15 K16 S17 A18 F28 D31 N111 K112 D114 L115 S141
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:1x1s, PDBe:1x1s, PDBj:1x1s
PDBsum1x1s
PubMed15994326
UniProtO08989|RASM_MOUSE Ras-related protein M-Ras (Gene Name=Mras)

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