Structure of PDB 1wvc Chain A

Receptor sequence
>1wvcA (length=254) Species: 220341 (Salmonella enterica subsp. enterica serovar Typhi str. CT18) [Search protein sequence]
ASKAVILAGGLGTRLSEETIVKPKPMVEIGGKPILWHIMKMYSVHGIKDF
IICCGYKGYVIKEYFANYFLHMSDVTFHMAENRMEVHHKRVEPWNVTLVD
TGDSSMTGGRLKRVAEYVKDDEAFLFTYGDGVADLDIKATIDFHKAHGKK
ATLTATFPPGRGALDIQAGQVRSFQKGDGAMINGGFFVLNPSVIDLIDND
ATTWEQEPLMTLAQQGELMAFEHPGFWQPMDTLRDKVYLEGLWEKGKAPW
KTWE
3D structure
PDB1wvc Kinetic and structural analysis of alpha-D-Glucose-1-phosphate cytidylyltransferase from Salmonella typhi.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.33: glucose-1-phosphate cytidylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D131 D236 D130 D231
BS02 CTP A L8 A9 G10 G11 G13 T14 R15 K25 S106 R111 G130 D131 L7 A8 G9 G10 G12 T13 R14 K24 S105 R110 G129 D130 PDBbind-CN: -logKd/Ki=4.46,Ki=35uM
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
GO:0047343 glucose-1-phosphate cytidylyltransferase activity
Biological Process
GO:0009058 biosynthetic process
GO:0009103 lipopolysaccharide biosynthetic process
GO:0009243 O antigen biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1wvc, PDBe:1wvc, PDBj:1wvc
PDBsum1wvc
PubMed15634670
UniProtQ8Z5I4|RFBF_SALTI Glucose-1-phosphate cytidylyltransferase (Gene Name=rfbF)

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