Structure of PDB 1wta Chain A

Receptor sequence
>1wtaA (length=273) Species: 272557 (Aeropyrum pernix K1) [Search protein sequence]
EITRPPGVRAHVGVIGGSGLYDPGIVENPVEVKVSTPYGNPSDFIVVGDV
AGVKVAFLPRHGRGHRIPPHAINYRANIWALKALGVKWVISVSAVGSLRE
DYRPGDFVVPDQFIDMTKNRRHYTFYDGPVTVHVSMADPFCEDLRQRLID
SGRRLGYTVHERGTYVCIEGPRFSTRAESRVWKDVFKADIIGMTLVPEIN
LACEAQLCYATLAMVTDYDVWADRPVTAEEVERVMISNVERARRMLYDVI
PKLAGEPELERCSCCRALDTAAI
3D structure
PDB1wta Crystal Structure of 5'-Deoxy-5'-methylthioadenosine from Aeropyrum pernix (R32 form)
ChainA
Resolution1.78 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D219 D221
Catalytic site (residue number reindexed from 1) D217 D219
Enzyme Commision number 2.4.2.28: S-methyl-5'-thioadenosine phosphorylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADE A V97 G98 F175 I193 D219 D221 V95 G96 F173 I191 D217 D219
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016757 glycosyltransferase activity
GO:0016763 pentosyltransferase activity
GO:0017061 S-methyl-5-thioadenosine phosphorylase activity
Biological Process
GO:0006166 purine ribonucleoside salvage
GO:0009116 nucleoside metabolic process
GO:0019509 L-methionine salvage from methylthioadenosine
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:1wta, PDBe:1wta, PDBj:1wta
PDBsum1wta
PubMed
UniProtQ9YAQ8|MTAP_AERPE S-methyl-5'-thioadenosine phosphorylase (Gene Name=mtnP)

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