Structure of PDB 1wrk Chain A

Receptor sequence
>1wrkA (length=82) Species: 9606 (Homo sapiens) [Search protein sequence]
IYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPT
PEELQEMIDEVDEDGSGTVDFDEFLVMMVRSM
3D structure
PDB1wrk Crystal structure of the N-terminal domain of human cardiac troponin C in complex with trifluoperazine
ChainA
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A D65 D67 S69 T71 E76 D62 D64 S66 T68 E73
BS02 TFP A M45 L48 Q50 M80 M42 L45 Q47 M77
BS03 TFP A F27 L48 M81 S84 F24 L45 M78 S81
BS04 TFP A E15 E19 F20 E12 E16 F17
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:1wrk, PDBe:1wrk, PDBj:1wrk
PDBsum1wrk
PubMed
UniProtP63316|TNNC1_HUMAN Troponin C, slow skeletal and cardiac muscles (Gene Name=TNNC1)

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