Structure of PDB 1wor Chain A

Receptor sequence
>1worA (length=362) Species: 2336 (Thermotoga maritima) [Search protein sequence]
MKRTPLFEKHVELGAKMVDFAGWEMPLYYTSIFEEVMAVRKSVGMFDVSH
MGEFLVKGPEAVSFIDFLITNDFSSLPDGKAIYSVMCNENGGIIDDLVVY
KVSPDEALMVVNAANIEKDFNWIKSHSKNFDVEVSNISDTTALIAFQGPK
AQETLQELVEDGLEEIAYYSFRKSIVAGVETLVSRTGYTGEDGFELMLEA
KNAPKVWDALMNLLRKIDGRPAGLGARDVCRLEATYLLYGQDMDENTNPF
EVGLSWVVKLNKDFVGKEALLKAKEKVERKLVALELSGKRIARKGYEVLK
NGERVGEITSGNFSPTLGKSIALALVSKSVKIGDQLGVVFPGGKLVEALV
VKKPFYRGSVRR
3D structure
PDB1wor Crystal Structure of T-protein of the Glycine Cleavage System: Cofactor binding, insights into H-protein recognition, and molecular basis for understanding nonketotic hyperglycinemia
ChainA
Resolution1.95 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D96
Catalytic site (residue number reindexed from 1) D96
Enzyme Commision number 2.1.2.10: aminomethyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RED A F20 L224 R227 D228 L238 F20 L224 R227 D228 L238
Gene Ontology
Molecular Function
GO:0004047 aminomethyltransferase activity
GO:0008483 transaminase activity
Biological Process
GO:0006546 glycine catabolic process
GO:0019464 glycine decarboxylation via glycine cleavage system
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005960 glycine cleavage complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1wor, PDBe:1wor, PDBj:1wor
PDBsum1wor
PubMed15355973
UniProtQ9WY54|GCST_THEMA Aminomethyltransferase (Gene Name=gcvT)

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