Structure of PDB 1wc5 Chain A

Receptor sequence
>1wc5A (length=193) Species: 118562 (Arthrospira platensis) [Search protein sequence]
MRPEPRLITILFSDIVGFTRMSNALQSQGVAELLNEYLGEMTRAVFENQG
TVDKFVGDAIMALYGAPEEMSPSEQVRRAIATARQMLVALEKLNQGWQER
GLVGRVPPVRFRCGIHQGMAVVGLFGSQERSDFTAIGPSVNIAARLQEAT
APNSIMVSAMVAQYVPDEEIIKREFLELKGIDEPVMTCVINPN
3D structure
PDB1wc5 Bicarbonate Activation of Adenylyl Cyclase Via Promotion of Catalytic Active Site Closure and Metal Recruitment
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 APC A D1017 I1018 G1020 F1021 T1022 V1059 G1060 D1061 D14 I15 G17 F18 T19 V56 G57 D58 MOAD: Ki=0.3mM
BS02 CA A D1017 I1018 D1061 D14 I15 D58
BS03 APC A K1057 M1064 V1145 N1146 R1150 K54 M61 V140 N141 R145 MOAD: Ki=0.3mM
Gene Ontology
Biological Process
GO:0009190 cyclic nucleotide biosynthetic process
GO:0035556 intracellular signal transduction

View graph for
Biological Process
External links
PDB RCSB:1wc5, PDBe:1wc5, PDBj:1wc5
PDBsum1wc5
PubMed15619637
UniProtO32393

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