Structure of PDB 1w9k Chain A

Receptor sequence
>1w9kA (length=719) Species: 44689 (Dictyostelium discoideum) [Search protein sequence]
DPIHDRTSDYHKYLKVKQGDDKRYIWYNPDPKERDSYECGEIVSETSDSF
TFKTVDGQDRQVKKDDANQRNPIKFDGVEDMSELSYLNEPAVFHNLRVRY
NQDLIYTYSGLFLVAVNPFKRIPIYTQEMVDIFKGRRRNEVAPHIFAISD
VAYRSMLDDRQNQSLLITGESGAGKTENTKKVIQYLASVAGRGVLEQQIL
QANPILEAFGNAKTTRNNNSSRFGKFIEIQFNSAGFISGASIQSYLLEKS
RVVFQSETERNYHIFYQLLAGATAEEKKALHLAGPESFNYLNQSGCVDIK
GVSDSEEFKITRQAMDIVGFSQEEQMSIFKIIAGILHLGNIKFEKGAGEG
AVLKDKTALNAASTVFGVNPSVLEKALMEPRILAGRDLVAQHLNVEKSSS
SRDALVKALYGRLFLWLVKKINNVLCEERKAYFIGVLDIEGFEIFKVNSF
EQLCINYTNEKLQQFFNHHMFKLEQEEYLKEKINWTFIDFGLDSQATIDL
IDGRQPPGILALLDEQSVFPNATDNTLITKLHSHFSKKNAKYEEPRFSKT
EFGVTHYAGQVMYEIQDWLEKNKDPLQQDLELCFKDSSDNVVTKLFNDPN
IASRAKFITVAAQYKEQLASLMATLETTNPHFVRCIIPNNKQLPAKLEDK
VVLDQLRCNGVLEGIRITRKGFPNRIIYADFVKEDSQKATDAVLKHLDPE
QFRFGITKIFFRAGQLARI
3D structure
PDB1w9k Structure-Function Analysis of Myosin II Backdoor Mutants
ChainA
Resolution2.05 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) S181 G182 T186 N233 S236 S237 G457 E459
Catalytic site (residue number reindexed from 1) S171 G172 T176 N217 S220 S221 G441 E443
Enzyme Commision number 3.6.4.1: Transferred entry: 5.6.1.8.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A T186 S237 T176 S221
BS02 ADP A N127 P128 G182 G184 K185 T186 E187 N233 N117 P118 G172 G174 K175 T176 E177 N217
BS03 BEF A S181 K185 N233 S236 S237 S171 K175 N217 S220 S221
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:1w9k, PDBe:1w9k, PDBj:1w9k
PDBsum1w9k
PubMed
UniProtP08799|MYS2_DICDI Myosin-2 heavy chain (Gene Name=mhcA)

[Back to BioLiP]