Structure of PDB 1w9j Chain A

Receptor sequence
>1w9jA (length=728) Species: 44689 (Dictyostelium discoideum) [Search protein sequence]
MNPIHDRTSDYHKYLKVKQGDSDLFKLTVSDKRYIWYNPDPKERDSYECG
EIVSETSDSFTFKTVDGQDRQVKKDDANQRNPIKFDGVEDMSELSYLNEP
AVFHNLRVRYNQDLIYTYSGLFLVAVNPFKRIPIYTQEMVDIFKGRRRNE
VAPHIFAISDVAYRSMLDDRQNQSLLITGESGAGKTENTKKVIQYLASVA
GRGVLEQQILQANPILEAFGNAKTTRNNNSSRFGKFIEIQFNSAGFISGA
SIQSYLLEKSRVVFQSETERNYHIFYQLLAGATAEEKKALHLAGPESFNY
LNQSGCVDIKGVSDSEEFKITRQAMDIVGFSQEEQMSIFKIIAGILHLGN
IKFEKGAGEGAVLKDKTALNAASTVFGVNPSVLEKALMEPRILAGRDLVA
QHLNVEKSSSSRDALVKALYGRLFLWLVKKINNVLCQERKAYFIGVLDIY
GFEIFKVNSFEQLCINYTNEKLQQFFNHHMFKLEQEEYLKEKINWTFIDF
GLDSQATIDLIDGRQPPGILALLDEQSVFPNATDNTLITKLHSHFSKKNA
KYEEPRFSKTEFGVTHYAGQVMYEIQDWLEKNKDPLQQDLELCFKDSSDN
VVTKLFNDPNIASRAKKGANFITVAAQYKEQLASLMATLETTNPHFVRCI
IPNNKQLPAKLEDKVVLDQLRCNGVLEGIRITRKGFPNRIIYADFVKRYS
QKATDDPEQYRFGITKIFFRAGQLARIE
3D structure
PDB1w9j Structure-Function Analysis of Myosin II Backdoor Mutants
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S181 G182 T186 N233 S236 S237 G457 E459
Catalytic site (residue number reindexed from 1) S181 G182 T186 N227 S230 S231 G451 E453
Enzyme Commision number 3.6.4.1: Transferred entry: 5.6.1.8.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A T186 S237 T186 S231
BS02 ADP A N127 P128 F129 G182 G184 K185 T186 E187 N233 N127 P128 F129 G182 G184 K185 T186 E187 N227
BS03 ALF A S181 K185 N233 S236 S237 G457 S181 K185 N227 S230 S231 G451
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:1w9j, PDBe:1w9j, PDBj:1w9j
PDBsum1w9j
PubMed
UniProtP08799|MYS2_DICDI Myosin-2 heavy chain (Gene Name=mhcA)

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