Structure of PDB 1w9i Chain A

Receptor sequence
>1w9iA (length=702) Species: 44689 (Dictyostelium discoideum) [Search protein sequence]
NPIHDRTSDYHKYLKVKQGDKRYIWYNPDPKERDSYECGEIVSETSDSFT
FKTVDGQDRQVKKDDANQRNPIKFDGVEDMSELSYLNEPAVFHNLRVRYN
QDLIYTYSGLFLVAVNPFKRIPIYTQEMVDIFKGRRRNEVAPHIFAISDV
AYRSMLDDRQNQSLLITGESGAGKTENTKKVIQYLASVAGRGVLEQQILQ
ANPILEAFGNAKTTRNNNSSRFGKFIEIQFNSAGFISGASIQSYLLEKSR
VVFQSETERNYHIFYQLLAGATAEEKKALHLAGPESFNYLNQSGCVDIKG
VSDSEEFKITRQAMDIVGFSQEEQMSIFKIIAGILHLGNIKFEKGAGEGA
VLKDKTALNAASTVFGVNPSVLEKALMEPRILAGRDLVAQHLNVEKSSSS
RDALVKALYGRLFLWLVKKINNVLCQERKAYFIGVLDIYGFEIFKVNSFE
QLCINYTNEKLQQFFNHHMFKLEQEEYLKEKINWTFIDFGLDSQATIDLI
DGRQPPGILALLDEQSVFPNATDNTLITKLHSHFSKKNAKYEEPRFSKTE
FGVTHYAGQVMYEIQDWLEKNKDPLQQDLELCFKDSSDNVVTKLFNDPNI
ASRAKKGANFITVAAQYKEQLASLMATLETTNPHFVRCIIPNNKQLPAKL
EDKVVLDQLRCNGVLEGIRITRKGFPNRIIYADQFRFGITKIFFRAGQLA
RI
3D structure
PDB1w9i Structure-Function Analysis of Myosin II Backdoor Mutants
ChainA
Resolution1.75 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S181 G182 T186 N233 S236 S237 G457 E459
Catalytic site (residue number reindexed from 1) S170 G171 T175 N216 S219 S220 G440 E442
Enzyme Commision number 3.6.4.1: Transferred entry: 5.6.1.8.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A T186 S237 I754 T175 S220 I702
BS02 ADP A N127 P128 G182 G184 K185 T186 E187 N233 N116 P117 G171 G173 K174 T175 E176 N216
BS03 BEF A S181 K185 N233 S236 S237 S170 K174 N216 S219 S220
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:1w9i, PDBe:1w9i, PDBj:1w9i
PDBsum1w9i
PubMed
UniProtP08799|MYS2_DICDI Myosin-2 heavy chain (Gene Name=mhcA)

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