Structure of PDB 1w80 Chain A

Receptor sequence
>1w80A (length=248) Species: 10090 (Mus musculus) [Search protein sequence]
PGILAPLAPGSEDNFARFVCKNNGVLFENQLLQIGLKSEFRQNLGRMFIF
YGNKTSTQFLNFTPTLICADDLQTNLNLQTKPVDPTVDGGAQVQQVINIE
CISDFTEAPVLNIQFRYGGTFQNVSVKLPITLNKFFQPTEMASQDFFQRW
KQLSNPQQEVQNIFKAKHPMDTEITKAKIIGFGSALLEEVDPNPANFVGA
GIIHTKTTQIGCLLRLEPNLQAQMYRLTLRTSKDTVSQRLCELLSEQF
3D structure
PDB1w80 Evolving Nature of the Ap2 Alpha-Appendage Hub During Clathrin-Coated Vesicle Endocytosis.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A N713 G714 G725 L726 K727 F740 G742 N743 G780 Q782 N23 G24 G35 L36 K37 F50 G52 N53 G90 Q92
BS02 peptide A F836 F837 W840 K841 R905 E907 N909 R916 F146 F147 W150 K151 R215 E217 N219 R226
BS03 CO3 A K841 R920 K151 R230
BS04 CO3 A R731 Q732 R41 Q42
BS05 CO3 A N719 Q720 N29 Q30
Gene Ontology
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0030117 membrane coat
GO:0030131 clathrin adaptor complex

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Biological Process
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Cellular Component
External links
PDB RCSB:1w80, PDBe:1w80, PDBj:1w80
PDBsum1w80
PubMed15496985
UniProtP17427|AP2A2_MOUSE AP-2 complex subunit alpha-2 (Gene Name=Ap2a2)

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