Structure of PDB 1w77 Chain A

Receptor sequence
>1w77A (length=212) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
MEKSVSVILLAGGSMPKQYIPLLGQPIALYSFFTFSRMPEVKEIVVVCDP
FFRDIFEEYEESIDVDLRFAIPGKERQDSVYSGLQEIDVNSELVCIHDSA
RPLVNTEDVEKVLKDGSAVGAAVLGVPAKATIKEVNSDSLVVTLWEMQTP
QVIKPELLKKGFELVKSEGLEVTDVSIVEYLKHPVYVSQGSYTNIKVTTP
DDLLLAERILSE
3D structure
PDB1w77 The Crystal Structure of a Plant 2C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase Exhibits a Distinct Quaternary Structure Compared to Bacterial Homologues and a Possible Role in Feedback Regulation for Cytidine Monophosphate.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.60: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CU A E138 E141 E57 E60
BS02 C5P A L84 A85 G86 G87 G154 K155 E156 S160 D179 K284 L10 A11 G12 G13 G73 K74 E75 S79 D98 K196
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0050518 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GO:0070567 cytidylyltransferase activity
Biological Process
GO:0008299 isoprenoid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1w77, PDBe:1w77, PDBj:1w77
PDBsum1w77
PubMed16478479
UniProtP69834|ISPD_ARATH 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic (Gene Name=ISPD)

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