Structure of PDB 1w66 Chain A

Receptor sequence
>1w66A (length=218) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
GAMAGSIRSKLSAIDVRQLGTVDYRTAWQLQRELADARVAGGADTLLLLE
HPAVYTAGRRTETHERPIDGTPVVDTDRGGKITWHGPGQLVGYPIIGLAE
PLDVVNYVRRLEESLIQVCADLGLHAGRVDGRSGVWLPGRPARKVAAIGV
RVSRATTLHGFALNCDCDLAAFTAIVPCGISDAAVTSLSAELGRTVTVDE
VRATVAAAVCAALDGVLP
3D structure
PDB1w66 The Mycobacterium Tuberculosis Lipb Enzyme Functions as a Cysteine/Lysine Dyad Acyltransferase.
ChainA
Resolution1.08 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.181: lipoyl(octanoyl) transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DKA A R76 G78 K79 A145 G158 F159 C176 R78 G80 K81 A147 G160 F161 C178
Gene Ontology
Molecular Function
GO:0016746 acyltransferase activity
GO:0033819 lipoyl(octanoyl) transferase activity
Biological Process
GO:0009107 lipoate biosynthetic process
GO:0009249 protein lipoylation
GO:0036211 protein modification process
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1w66, PDBe:1w66, PDBj:1w66
PDBsum1w66
PubMed16735476
UniProtP9WK83|LIPB_MYCTU Octanoyltransferase (Gene Name=lipB)

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