Structure of PDB 1w3l Chain A

Receptor sequence
>1w3lA (length=300) Species: 76935 (Salipaludibacillus agaradhaerens) [Search protein sequence]
SVVEEHGQLSISNGELVNERGEQVQLKGMSSHGLQWYGQFVNYESMKWLR
DDWGINVFRAAMYTSSGGYIDDPSVKEKVKEAVEAAIDLDIYVIIDWHIL
SDNDPNIYKEEAKDFFDEMSELYGDYPNVIYEIANEPNGSDVTWGNQIKP
YAEEVIPIIRNNDPNNIIIVGTGTWSQDVHHAADNQLADPNVMYAFHFYA
GTHGQNLRDQVDYALDQGAAIFVSEWGTSAATGDGGVFLDEAQVWIDFMD
ERNLSWANWSLTHKDESSAALMPGANPTGGWTEAELSPSGTFVREKIRES
3D structure
PDB1w3l Structural, Thermodynamic, and Kinetic Analyses of Tetrahydrooxazine-Derived Inhibitors Bound to {Beta}-Glucosidases
ChainA
Resolution1.04 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.4: cellulase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGC A H35 W39 Y66 W262 K267 E269 H32 W36 Y63 W259 K264 E266 PDBbind-CN: -logKd/Ki=6.28,Ki=0.52uM
BS02 BGC A W39 K267 W36 K264 PDBbind-CN: -logKd/Ki=6.28,Ki=0.52uM
BS03 OXZ A Y66 H101 E139 Y202 E228 A234 T235 G236 W262 Y63 H98 E136 Y199 E225 A231 T232 G233 W259 PDBbind-CN: -logKd/Ki=6.28,Ki=0.52uM
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
Biological Process
GO:0000272 polysaccharide catabolic process
GO:0005975 carbohydrate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1w3l, PDBe:1w3l, PDBj:1w3l
PDBsum1w3l
PubMed15356002
UniProtO85465|GUN5_SALAG Endoglucanase 5A (Gene Name=cel5A)

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