Structure of PDB 1w0u Chain A

Receptor sequence
>1w0uA (length=55) Species: 9606 (Homo sapiens) [Search protein sequence]
KKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMK
RLGMN
3D structure
PDB1w0u How the Human Telomeric Proteins Trf1 and Trf2 Recognize Telomeric DNA: A View from High-Resolution Crystal Structures
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A K447 G468 W470 K488 R492 K2 G23 W25 K43 R47
BS02 dna A K447 Q448 K449 W450 R482 M486 D489 R490 T493 K2 Q3 K4 W5 R37 M41 D44 R45 T48
Gene Ontology
Molecular Function
GO:0042162 telomeric DNA binding
Biological Process
GO:0000723 telomere maintenance
GO:0031848 protection from non-homologous end joining at telomere
Cellular Component
GO:0000781 chromosome, telomeric region
GO:0005634 nucleus

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1w0u, PDBe:1w0u, PDBj:1w0u
PDBsum1w0u
PubMed15608617
UniProtQ15554|TERF2_HUMAN Telomeric repeat-binding factor 2 (Gene Name=TERF2)

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