Structure of PDB 1vpa Chain A

Receptor sequence
>1vpaA (length=221) Species: 2336 (Thermotoga maritima) [Search protein sequence]
HHMNVAILLAAGKGERMSENVPKQFLEIEGRMLFEYPLSTFLKSEAIDGV
VIVTRREWFEVVEKRVFHEKVLGIVEGGDTRSQSVRSALEFLEKFSPSYV
LVHDSARPFLRKKHVSEVLRRARETGAATLALKNSDALVRVENDRIEYIP
RKGVYRILTPQAFSYEILKKAHENGGEWADDTEPVQKLGVKIALVEGDPL
CFKVTFKEDLELARIIAREWE
3D structure
PDB1vpa Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (TM1393) from Thermotoga maritima at 2.67 A resolution
ChainA
Resolution2.67 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.60: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CTP A L7 A9 G10 K11 G12 E13 R14 K21 T78 R79 S82 D102 S103 K201 L9 A11 G12 K13 G14 E15 R16 K23 T80 R81 S84 D104 S105 K203
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016779 nucleotidyltransferase activity
GO:0050518 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GO:0070567 cytidylyltransferase activity
Biological Process
GO:0008299 isoprenoid biosynthetic process
GO:0019288 isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:1vpa, PDBe:1vpa, PDBj:1vpa
PDBsum1vpa
PubMed
UniProtQ9X1B3|ISPD_THEMA 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (Gene Name=ispD)

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