Structure of PDB 1vom Chain A

Receptor sequence
>1vomA (length=730) Species: 44689 (Dictyostelium discoideum) [Search protein sequence]
NPIHDRTSDYHKYLKVKQGDSDLFKLTVSDKRYIWYNPDPDERDSYECGE
IVSETSDSFTFKTVDGQDRQVKKDDANQRNPIKFDGVEDMSELSYLNEPA
VFHNLRVRYNQDLIYTYSGLFLVAVNPFKRIPIYTQEMVDIFKGRRRNEV
APHIFAISDVAYRSMLDDRQNQSLLITGESGAGKTENTKKVIQYLASVAG
RNQGVLEQQILQANPILEAFGNAKTTRNNNSSRFGKFIEIQFNNAGFISG
ASIQSYLLEKSRVVFQSETERNYHIFYQLLAGATAEEKKALHLAGPESFN
YLNQSGCVDIKGVSDEDEFKITRQAMDIVGFSQEEQMSIFKIIAGILHLG
NIKFEKGAGEGAVLKDKTALNAASTVFGVNPSVLEKALMEPRILAGRDLV
AQHLNVEKSSSSRDALVKALYGRLFLWLVKKINNVLCSERAAYFIGVLDI
SGFEIFKVNSFEQLCINYTNEKLQQFFNHHMFKVEQEEYLKEKINWTFID
FGLDSQATIDLIDGRQPPGILALLDEQSVFPNATDNTLITKLHSHFSKKN
AKYEEPRFSKTEFGVTHYAGQVMYEIQDWLEKNKDPLQQDLELCFKDSSD
NVVTKLFNDPNIASRAKKGANFITVAAQYKEQLASLMATLETTNPHFVRC
IIPNNKQLPAKLEDKVVLDQLRCNGVLEGIRITRKGFPNRIIYADFVKRY
YLLAPVPRDQKATNIDPEQYRFGITKIFFR
3D structure
PDB1vom X-ray structure of the magnesium(II).ADP.vanadate complex of the Dictyostelium discoideum myosin motor domain to 1.9 A resolution.
ChainA
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S181 G182 T186 N233 S236 S237 G457 E459
Catalytic site (residue number reindexed from 1) S180 G181 T185 N228 S231 S232 G452 E454
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG A T186 S237 T185 S232
BS02 VO4 A S181 G182 K185 N233 S236 S237 S456 G457 S180 G181 K184 N228 S231 S232 S451 G452
BS03 ADP A N127 P128 F129 K130 G182 G184 K185 T186 E187 N233 N126 P127 F128 K129 G181 G183 K184 T185 E186 N228
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:1vom, PDBe:1vom, PDBj:1vom
PDBsum1vom
PubMed8611530
UniProtP08799|MYS2_DICDI Myosin-2 heavy chain (Gene Name=mhcA)

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