Structure of PDB 1vol Chain A

Receptor sequence
>1volA (length=204) Species: 9606 (Homo sapiens) [Search protein sequence]
AMMNAFKEITTMADRINLPRNKVDRTNNLFRQAYEQKSLKGRANDAIASA
CLYIACRQEGVPRTFKEICAVSRISKKEIGRCFKLILKALETSVDLITTG
DFMSRFCSNLCLPKQVQMAATHIARKAVELDLVPGRSPISVAAAAIYMAS
QASAEKRTQKEIGDIAGVADVTIRQSYRLIYPRAPDLFPTDFKFDTPVDK
LPQL
3D structure
PDB1vol Crystal structure of a TFIIB-TBP-TATA-element ternary complex.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A G153 K189 R193 G41 K77 R81
BS02 dna A K152 G247 R248 S249 S252 A281 T284 K40 G135 R136 S137 S140 A169 T172
Gene Ontology
Molecular Function
GO:0017025 TBP-class protein binding
Biological Process
GO:0006352 DNA-templated transcription initiation
GO:0070897 transcription preinitiation complex assembly

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Molecular Function

View graph for
Biological Process
External links
PDB RCSB:1vol, PDBe:1vol, PDBj:1vol
PDBsum1vol
PubMed7675079
UniProtQ00403|TF2B_HUMAN Transcription initiation factor IIB (Gene Name=GTF2B)

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