Structure of PDB 1v8j Chain A

Receptor sequence
>1v8jA (length=337) Species: 10090 (Mus musculus) [Search protein sequence]
PNWEFARMIKEFRVTMECSPLTPIEEHRICVCVRKRPLNKQELAKKEIDV
ISVPSKCLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFTAR
PLVQTIFEGGKATCFAYGQTGSGKTHTMGGDQNASKGIYAMASRDVFLLK
NQPRYRNLNLEVYVTFFEIYNGKVFDLLNKKAKLRVLEDSRQQVQVVGLQ
EYLVTCADDVIKMINMGSACRTSGNSNSSRSHACFQILLRTKGRLHGKFS
LVDLAGNERRQTRMEGAEINKSLLALKECIRALGQFRESKLTQVLRDSFI
GENSRTCMIAMISPGISSCEYTLNTLRYADRVKELSH
3D structure
PDB1v8j A common mechanism for microtubule destabilizers-M type kinesins stabilize curling of the protofilament using the class-specific neck and loops.
ChainA
Resolution3.24 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A R78 T164 G165 S166 G167 K168 T169 H170 R34 T120 G121 S122 G123 K124 T125 H126
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
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Biological Process
External links
PDB RCSB:1v8j, PDBe:1v8j, PDBj:1v8j
PDBsum1v8j
PubMed14980225
UniProtQ922S8|KIF2C_MOUSE Kinesin-like protein KIF2C (Gene Name=Kif2c)

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