Structure of PDB 1uz8 Chain A

Receptor sequence

>1uz8A (length=218) Species: 10090 (Mus musculus) [Search protein sequence]

DIVMTQAAFSNPVTLGTSASISCRSSKSLLYSNGITYLYWYLQKPGQSPQ
LLIYQMSNLASGVPDRFSSSGSGTDFTLRISRVEAEDVGVYYCAQNLEVP
WTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDIN
VKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCE
ATHKTSTSPIVKSFNRNE

3D structure

PDB

1uz8 Structure of an Anti-Lewis X Fab Fragment in Complex with its Lewis X Antigen

Chain

Resolution

1.8 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MAG	A	Y32 N91 L92 V94	Y37 N96 L97 V99	PDBbind-CN: -logKd/Ki=4.96,Kd=11uM
BS02	FUC	A	Y32 Y34 Q50 N91	Y37 Y39 Q55 N96	PDBbind-CN: -logKd/Ki=4.96,Kd=11uM

External links

PDB	RCSB:1uz8, PDBe:1uz8, PDBj:1uz8
PDBsum	1uz8
PubMed	15242599

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