Structure of PDB 1uwv Chain A

Receptor sequence
>1uwvA (length=417) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
QIITVSVNDLDSFGQGVARHNGKTLFIPGLLPQENAEVTVTEDKKQYARA
KVVRRLSDSPERETPRCPHFGVCGGCQQQHASVDLQQRSKSAALARLMKH
DVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVKQCPI
LAPQLEALLPKVRACLGSLQAMRHLGHVELVQATSGTLMILRHTAPLSSA
DREKLERFSHSEGLDLYLAPDSEILETVSGEMPWYDSNGLRLTFSPRDFI
QVNAGVNQKMVARALEWLDVQPEDRVLDLFCGMGNFTLPLATQAASVVGV
EGVPALVEKGQQNARLNGLQNVTFYHENLEEDVTKQPWAKNGFDKVLLDP
ARAGAAGVMQQIIKLEPIRIVYVSCNPATLARDSEALLKAGYTIARLAML
DMFPHTGHLESMVLFSR
3D structure
PDB1uwv Crystal Structure of Ruma, an Iron-Sulfur Cluster Containing E. Coli Ribosomal RNA 5-Methyluridine Methyltransferase.
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.190: 23S rRNA (uracil(1939)-C(5))-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 A C81 C87 G89 C90 Q93 F148 C162 P163 I164 R431 C67 C73 G75 C76 Q79 F134 C148 P149 I150 R417
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005506 iron ion binding
GO:0008168 methyltransferase activity
GO:0008173 RNA methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0070041 rRNA (uridine-C5-)-methyltransferase activity
Biological Process
GO:0006364 rRNA processing
GO:0006396 RNA processing
GO:0009451 RNA modification
GO:0031167 rRNA methylation
GO:0032259 methylation
GO:0070475 rRNA base methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:1uwv, PDBe:1uwv, PDBj:1uwv
PDBsum1uwv
PubMed15016356
UniProtP55135|RLMD_ECOLI 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD (Gene Name=rlmD)

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