Structure of PDB 1up3 Chain A

Receptor sequence
>1up3A (length=293) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
ANPLAGKPFYVDPASAAMVAARNANPPNAELTSVANTPQSYWLDQAFPPA
TVGGTVARYTGAAQAAGAMPVLTLYGIPHRDCGSYASGGFATGTDYRGWI
DAVASGLGSSPATIIVEPDALAMADCLSPDQRQERFDLVRYAVDTLTRDP
AAAVYVDAGHSRWLSAEAMAARLNDVGVGRARGFSLNVSNFYTTDEEIGY
GEAISGLTNGSHYVIDTSRNGAGPAPDAPLNWCNPSGRALGAPPTTATAG
AHADAYLWIKRPGESDGTCGRGEPQAGRFVSQYAIDLAHNAGQ
3D structure
PDB1up3 Mycobacterium Tuberculosis Strains Possess Functional Cellulases.
ChainA
Resolution1.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y162 R167 D168 S174 D206 D353
Catalytic site (residue number reindexed from 1) Y75 R80 D81 S87 D119 D266
Enzyme Commision number 3.2.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGC A H247 W250 W319 H160 W163 W232
BS02 BGC A D168 D206 N277 W319 D81 D119 N190 W232
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
Biological Process
GO:0030245 cellulose catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1up3, PDBe:1up3, PDBj:1up3
PDBsum1up3
PubMed15824123
UniProtQ79G13

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