Structure of PDB 1uk8 Chain A

Receptor sequence
>1uk8A (length=271) Species: 294 (Pseudomonas fluorescens) [Search protein sequence]
NLEIGKSILAAGVLTNYHDVGEGQPVILIHGSGPGVSAYANWRLTIPALS
KFYRVIAPDMVGFGFTDRPENYNYSKDSWVDHIIGIMDALEIEKAHIVGN
AFGGGLAIATALRYSERVDRMVLMGAAGTRFDVTEGLNAVWGYTPSIENM
RNLLDIFAYDRSLVTDELARLRYEASIQPGFQESFSSMFPEPRQRWIDAL
ASSDEDIKTLPNETLIIHGREDQVVPLSSSLRLGELIDRAQLHVFGRCGH
WTQIEQTDRFNRLVVEFFNEA
3D structure
PDB1uk8 A Series of Crystal Structures of a meta-Cleavage Product Hydrolase from Pseudomonas fluorescens IP01 (CumD) Complexed with Various Cleavage Products
ChainA
Resolution1.6 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) S34 G35 G37 N102 A103 F104 G127 V142 R174 F187 D224 H252 W253
Catalytic site (residue number reindexed from 1) S32 G33 G35 N100 A101 F102 G125 V140 R172 F185 D222 H250 W251
Enzyme Commision number 3.7.1.9: 2-hydroxymuconate-6-semialdehyde hydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LEA A S34 A103 F104 L139 W143 H252 S32 A101 F102 L137 W141 H250
BS02 LEA A L233 G236 E237 L231 G234 E235
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:1uk8, PDBe:1uk8, PDBj:1uk8
PDBsum1uk8
PubMed15784976
UniProtP96965

[Back to BioLiP]