Structure of PDB 1uev Chain A

Receptor sequence
>1uevA (length=431) Species: 2234 (Archaeoglobus fulgidus) [Search protein sequence]
KVEEILEKALELVIPDEEEVRKGREAEEELRRRLDELGVEYVFVGSYARN
TWLKGSLEIDVFLLFPEEFSKEELRERGLEIGKAVLDSYEHPYVHGVVKG
VEVDVVPCYKLKEPKNIKSAVDRTPFHHKWLEGRIKGKENEVRLLKGFLK
ANGIYGAEYKVRGFSGYLCELLIVFYGSFLETVKNARRWTRRTVIDVAKG
EVRKGEEFFVVDPVDEKRNVAANLSLDNLARFVHLCREFMEAPSLGFFKP
KHPLEIEPERLRKIVEERGTAVFAVKFRKPDIVDDNLYPQLERASRKIFE
FLERENFMPLRSAFKASEEFCYLLFECQIKEISRVFRRMGPQFEDERNVK
KFLSRNRAFRPFIENGRWWAFEMRKFTTPEEGVRSYASTHWHTLGKNVGE
SIREYFEIISGEKLFKEPVTAELCEMMGVKD
3D structure
PDB1uev Divergent evolutions of trinucleotide polymerization revealed by an archaeal CCA-adding enzyme structure.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.72: CCA tRNA nucleotidyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A E59 D61 D110 E58 D60 D104
BS02 ATP A G46 S47 W53 L54 E59 D61 T130 H133 K152 Y161 G172 E176 G45 S46 W52 L53 E58 D60 T124 H127 K146 Y155 G166 E170
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0000287 magnesium ion binding
GO:0003723 RNA binding
GO:0004810 CCA tRNA nucleotidyltransferase activity
GO:0005524 ATP binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
GO:0160016 CCACCA tRNA nucleotidyltransferase activity
Biological Process
GO:0001680 tRNA 3'-terminal CCA addition
GO:0008033 tRNA processing
GO:0031123 RNA 3'-end processing
GO:0042245 RNA repair
GO:0106354 tRNA surveillance

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Molecular Function
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Biological Process
External links
PDB RCSB:1uev, PDBe:1uev, PDBj:1uev
PDBsum1uev
PubMed14592988
UniProtO28126|CCA_ARCFU CCA-adding enzyme (Gene Name=cca)

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