Structure of PDB 1u3i Chain A

Receptor sequence
>1u3iA (length=208) Species: 6183 (Schistosoma mansoni) [Search protein sequence]
EHIKVIYFDGRGRAESIRMTLVAAGVDYEDERISFQDWPKIKPTIPGGRL
PAVKVTDDHGHVKWMLESLAIARYMAKKHHMMGETDEEYYSVEKLIGQAE
DVEHEYHKTLMKPQEEKEKITKEILNGKVPVLFNMICESLKGSTGKLAVG
DKVTLADLVLIAVIDHVTDLDKGFLTGKYPEIHKHRENLLASSPRLAKYL
SNRPATPF
3D structure
PDB1u3i Crystallization and preliminary X-ray diffraction studies of a protective cloned 28 kDa glutathione S-transferase from Schistosoma mansoni
ChainA
Resolution1.89 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y10 R16 R21
Catalytic site (residue number reindexed from 1) Y7 R13 R18
Enzyme Commision number 2.5.1.18: glutathione transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH A Y10 R16 W41 K45 R52 L53 E70 S71 Y7 R13 W38 K42 R49 L50 E67 S68
Gene Ontology
Molecular Function
GO:0004364 glutathione transferase activity
GO:0016740 transferase activity
Biological Process
GO:0006749 glutathione metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1u3i, PDBe:1u3i, PDBj:1u3i
PDBsum1u3i
PubMed
UniProtP09792|GST28_SCHMA Glutathione S-transferase class-mu 28 kDa isozyme (Gene Name=GST28)

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