Structure of PDB 1u1n Chain A

Receptor sequence
>1u1nA (length=183) Species: 9606 (Homo sapiens) [Search protein sequence]
KEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGF
GFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKI
FVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHD
SVDKIVIQKYHTVNGHNCEVRKALSKQEMASAS
3D structure
PDB1u1n Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM).
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A Q12 K15 F17 G19 G20 D42 V44 M46 R55 F57 F59 E85 A89 V90 R92 S95 H101 Q5 K8 F10 G12 G13 D35 V37 M39 R48 F50 F52 E78 A82 V83 R85 S88 H94 PDBbind-CN: Kd=316nM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:1u1n, PDBe:1u1n, PDBj:1u1n
PDBsum1u1n
PubMed15342234
UniProtP09651|ROA1_HUMAN Heterogeneous nuclear ribonucleoprotein A1 (Gene Name=HNRNPA1)

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