Structure of PDB 1u18 Chain A

Receptor sequence
>1u18A (length=184) Species: 13249 (Rhodnius prolixus) [Search protein sequence]
KCTKNALAQTGFNKDKYFNGDVWYVTDYLDLEPDDVPKRYCAALAAGTAS
GKLKEALYCYDPKTQDTFYDVSELQEESPGKYTANFKKVEKNGNVKVDVT
SGNYYTFTVMYADDSSALIHTCLHKGNKDLGDLYAVLNRNKDTNAGDKVK
GAVTAASLKFSDFISTKDNKCEYDNVSLKSLLTK
3D structure
PDB1u18 1.96 A Crystal structure of H60C mutant of nitrophorin complexed with histamine
ChainA
Resolution1.96 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A Y29 K39 Y41 L58 F69 D71 F87 K89 Y106 L124 K126 Y28 K38 Y40 L57 F68 D70 F86 K88 Y105 L123 K125
BS02 HSM A D31 E33 L124 L131 D30 E32 L123 L130
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
GO:0051381 histamine binding
GO:0070026 nitric oxide binding
Biological Process
GO:0042311 vasodilation
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1u18, PDBe:1u18, PDBj:1u18
PDBsum1u18
PubMed
UniProtQ26239|NP1_RHOPR Nitrophorin-1

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