Structure of PDB 1txu Chain A

Receptor sequence
>1txuA (length=254) Species: 9606 (Homo sapiens) [Search protein sequence]
ETDRVSKEFIEFLKTFHKTGQEIYKQTKLFLEGMHYKRDLSIEEQSECAQ
DFYHNVAERMQTRGKVPPERVEKIMDQIEKYIMTRLYKYVFCPETTDDEK
KDLAIQKRIRALRWVTPQMLCVPVNEDIPEVSDMVVKAITDIIEMDSKRV
PRDKLACITKCSKHIFNAIKITKNEPASADDFLPTLIYIVLKGNPPRLQS
NIQYITRFCNPSRLMTGEDGYYFTNLCCAVAFIEKLDAQSLNLSQEDFDR
YMSG
3D structure
PDB1txu Structure, exchange determinants, and family-wide rab specificity of the tandem helical bundle and Vps9 domains of Rabex-5
ChainA
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D274 H297 D141 H164
Gene Ontology
Molecular Function
GO:0005085 guanyl-nucleotide exchange factor activity
Biological Process
GO:0016192 vesicle-mediated transport

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Molecular Function
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Biological Process
External links
PDB RCSB:1txu, PDBe:1txu, PDBj:1txu
PDBsum1txu
PubMed15339665
UniProtQ9UJ41|RABX5_HUMAN Rab5 GDP/GTP exchange factor (Gene Name=RABGEF1)

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