Structure of PDB 1tu4 Chain A

Receptor sequence
>1tu4A (length=169) Species: 9606 (Homo sapiens) [Search protein sequence]
GNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCL
DDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNW
VKELQRQASPNIVIALSGNKADLANKRAVDFQEAQSYADDNSLLFMETSA
KTSMNVNEIFMAIAKKLPK
3D structure
PDB1tu4 Structural basis of Rab5-Rabaptin5 interaction in endocytosis
ChainA
Resolution2.2 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP A A30 G32 K33 S34 S35 N133 K134 D136 S163 A164 K165 A16 G18 K19 S20 S21 N119 K120 D122 S149 A150 K151
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:1tu4, PDBe:1tu4, PDBj:1tu4
PDBsum1tu4
PubMed15378032
UniProtP20339|RAB5A_HUMAN Ras-related protein Rab-5A (Gene Name=RAB5A)

[Back to BioLiP]