Structure of PDB 1tqx Chain A

Receptor sequence
>1tqxA (length=221) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
LKAIIAPSVLASNISKLAEETQRMESLGAEWIHLDVMDMHFVPNLSFGPP
VINNLKKYTKSIFFDVHLMVEYPEKYVPLLKTSNQLTFHFEALNEDTERC
IQLAKEIRDNNLWCGISIKPKTDVQKLVPILDTNLINTVLVMTVEPGFGG
QSFMHDMMGKVSFLRKKYKNLNIQVDGGLNIETTEISASHGANIIVAGTS
IFNAEDPKYVIDTMRVSVQKY
3D structure
PDB1tqx Structure of a ribulose 5-phosphate 3-epimerase from Plasmodium falciparum.
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S11 H36 D38 M40 H70 M72 M145 D179
Catalytic site (residue number reindexed from 1) S8 H33 D35 M37 H67 M69 M142 D176
Enzyme Commision number 5.1.3.1: ribulose-phosphate 3-epimerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SO4 A G152 G181 G201 T202 G149 G178 G198 T199
BS02 ZN A H36 D38 H70 D179 H33 D35 H67 D176
Gene Ontology
Molecular Function
GO:0004750 D-ribulose-phosphate 3-epimerase activity
GO:0016853 isomerase activity
GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives
GO:0046872 metal ion binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006098 pentose-phosphate shunt
GO:0009052 pentose-phosphate shunt, non-oxidative branch
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1tqx, PDBe:1tqx, PDBj:1tqx
PDBsum1tqx
PubMed16304640
UniProtQ8I5L3

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