Structure of PDB 1tqh Chain A

Receptor sequence
>1tqhA (length=242) Species: 1422 (Geobacillus stearothermophilus) [Search protein sequence]
PPKPFFFEAGERAVLLLHGFTGNSADVRMLGRFLESKGYTCHAPIYKGHG
VPPEELVHTGPDDWWQDVMNGYEFLKNKGYEKIAVAGLSLGGVFSLKLGY
TVPIEGIVTMCAPMYIKSEETMYEGVLEYAREYKKREGKSEEQIEQEMEK
FKQTPMKTLKALQELIADVRDHLDLIYAPTFVVQARHDEMINPDSANIIY
NEIESPVKQIKWYEQSGHVITLDQEKDQLHEDIYAFLESLDW
3D structure
PDB1tqh Covalent reaction intermediate revealed in crystal structure of the Geobacillus stearothermophilus carboxylesterase Est30.
ChainA
Resolution1.63 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.1.1: carboxylesterase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 4PA A G24 F25 S94 L95 H223 G19 F20 S89 L90 H218
Gene Ontology
Molecular Function
GO:0016298 lipase activity
GO:0052689 carboxylic ester hydrolase activity
GO:0106435 carboxylesterase activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:1tqh, PDBe:1tqh, PDBj:1tqh
PDBsum1tqh
PubMed15327954
UniProtQ06174|EST_GEOSE Carboxylesterase (Gene Name=est)

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