Structure of PDB 1tiy Chain A

Receptor sequence
>1tiyA (length=157) Species: 1423 (Bacillus subtilis) [Search protein sequence]
MNHETFLKRAVTLACEGVNAGIGGPFGAVIVKDGAIIAEGQNNVTTSNDP
TAHAEVTAIRKACKVLGAYQLDDCILYTSCEPCPMCLGAIYWARPKAVFY
AAEHTDAAEAGFDDSFIYKEIDKPAEERTIPFYQVTLTEHLSPFQAWRNF
ANKKEYL
3D structure
PDB1tiy X-RAY STRUCTURE OF GUANINE DEAMINASE FROM BACILLUS SUBTILIS NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SR160
ChainA
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E55 E81 C83
Catalytic site (residue number reindexed from 1) E55 E81 C83
Enzyme Commision number 3.5.4.3: guanine deaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H53 C83 C86 H53 C83 C86
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008270 zinc ion binding
GO:0008892 guanine deaminase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0047974 guanosine deaminase activity
Biological Process
GO:0006144 purine nucleobase metabolic process
GO:0006147 guanine catabolic process
GO:0006152 purine nucleoside catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1tiy, PDBe:1tiy, PDBj:1tiy
PDBsum1tiy
PubMed
UniProtO34598|GUAD_BACSU Guanine deaminase (Gene Name=guaD)

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