Structure of PDB 1tg7 Chain A

Receptor sequence
>1tg7A (length=971) Species: 5081 (Penicillium sp.) [Search protein sequence]
LLQKYVTWDEHSIFVNGERLMIFSGEVHPYRLPVASLYIDIFEKVKALGF
NCVSFYVDWALLEGNPGHYSAEGIFDLQPFFDAAKEAGIYLLARPGPYIN
AEVSGGGFPGWLQRVDGILRTSDEAYLKATDNYASNIAATIAKAQITNGG
PIILYQPENEYSGACCGYNGFPDGSYMQYIEDHARDAGIVVPFISNDAWA
AGHNAPGTGAGAVDIYGHDSYPLGFDCANPSTWPSGNLPTYFHTSHEQQS
PSTPYSLVEFQGGAFDPWGGVGFAKCAALLNHEFERVFYKNDFSFGVAFL
NLYMIFGGTNWGNLGHPGGYTSYDYGSAISESRNITREKYSELKLLGNFA
KVSPGYLVANPGDLSTSTYTNTADLTVTPLLGSNSSASSFFVIRHSDYSS
QASVEYKLTVPTSAGNLTIPQLGGSLTLSGRDSKIHVTDYDVAGTNILYS
TAEVFTWKKFNNEKVLVLYGGPGEHHEFAVSGASSSSVVEGSSSGISSKK
VGKALVVAWDVSTARRIVQVGSLKVFLLDRNSAYNYWVPQVPTKGTAPGY
SNQETTASSIIVKAGYLVRSAYLDGNDLHIQADFNATTPIEVVGAPSGAK
NLVINGKKTQTKVDKNGIWSASVAYTAPKVQLPSLKSLKWKSVDTLPEAK
NTYDDSAWTSADHAYTNNSAHSLQTPTSLFASDYGYHTGALLFRGHFTAN
GKEKTFFVQTKGGTAYGHSIWINETYVGSWAGTSINDNNNATYTLPTLQS
GKNYVITVVIDNMGLDEDWTIGSEDMKNPRGIIQYSLSGQEASAISWKLT
GNLGGENYRDTVRGPLNEGGLYAERQGFHQPQPPTQKWDSSSPFTGLTKP
GIRFYSTSFDLDLPSGYDIPLYFNFGNSTSTPAAYRVQLYVNGYQYGKYV
NNIGPQTSFPVPEGILNYHGTNWLALSLWAQEDNGAKLDSFELINTTPVL
TSLGEVKSVNQPKYQARKGAY
3D structure
PDB1tg7 Crystal Structures of beta-Galactosidase from Penicillium sp. and its Complex with Galactose
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.23: beta-galactosidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN A E378 N571 E338 N531
BS02 MAN A E323 R326 E283 R286
BS03 MAN A D569 N571 D529 N531
BS04 MAN A A710 H711 A670 H671
BS05 BMA A T773 I775 T733 I735
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004565 beta-galactosidase activity
GO:0005534 galactose binding
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0000272 polysaccharide catabolic process
GO:0005975 carbohydrate metabolic process
GO:0005990 lactose catabolic process
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005773 vacuole

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1tg7, PDBe:1tg7, PDBj:1tg7
PDBsum1tg7
PubMed15491613
UniProtQ700S9|BGALA_PENSQ Beta-galactosidase A (Gene Name=lacA)

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