Structure of PDB 1tf6 Chain A

Receptor sequence

>1tf6A (length=179) Species: 8355 (Xenopus laevis) [Search protein sequence]

YKRYICSFADCGAAYNKNWKLQAHLCKHTGEKPFPCKEEGCEKGFTSLHH
LTRHSLTHTGEKNFTCDSDGCDLRFTTKANMKKHFNRFHNIKICVYVCHF
ENCGKAFKKHNQLKVHQFSHTQQLPYECPHEGCDKRFSLPSRLKRHEKVH
AGYPCKKDDSCSFVGKTWTLYLKHVAECH

3D structure

PDB

1tf6 Differing roles for zinc fingers in DNA recognition: structure of a six-finger transcription factor IIIA complex.

Chain

Resolution

3.1 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	A	Y24 W28 K29 K36 F54 H59 R62 F84 T85 N89 K92 R96 R151 R154 H155	Y15 W19 K20 K27 F45 H50 R53 F75 T76 N80 K83 R87 R142 R145 H146
BS02	dna	A	R12 Y13 K26 W28 H58 K87 K92 P149 S150	R3 Y4 K17 W19 H49 K78 K83 P140 S141
BS03	ZN	A	C15 C20 H33 H37	C6 C11 H24 H28
BS04	ZN	A	C45 C50 H63 H67	C36 C41 H54 H58
BS05	ZN	A	C80 H93 H98	C71 H84 H89
BS06	ZN	A	C107 C112 H125 H129	C98 C103 H116 H120
BS07	ZN	A	C137 C142 H155 H159	C128 C133 H146 H150
BS08	ZN	A	C164 H183 H188	C155 H174 H179

External links

PDB	RCSB:1tf6, PDBe:1tf6, PDBj:1tf6
PDBsum	1tf6
PubMed	9501194
UniProt	P03001\|TF3A_XENLA Transcription factor IIIA (Gene Name=gtf3a)

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