Structure of PDB 1tdk Chain A

Receptor sequence
>1tdkA (length=484) Species: 8714 (Gloydius halys) [Search protein sequence]
DRNPLEECFRETDYEEFLEIARNGLKATSNPKHVVVVGAGMSGLSAAYVL
SGAGHQVTVLEASERAGGRVRTYRNDKEDWYANLGPMRLPEKHRIVREYI
RKFGLQLNEFSQENDNAWYFIKNIRKRVGEVKKDPGVLKYPVKPSEEGKS
AGQLYEESLGKVVEELKRTNCSYILNKYDTYSTKEYLLKEGNLSPGAVDM
IGDLMNEDSGYYVSFPESLRHDDIFAYEKRFDEIVGGMDKLPTSMYRAIE
EKVHLNAQVIKIQKNAEKVTVVYQTPAKEMASVTADYVIVCTTSRATRRI
KFEPPLPPKKAHALRSVHYRSGTKIFLTCTKKFWEDEGIHGGKSTTDLPS
RFIYYPNHNFTSGVGVIIAYGIGDDANFFQALDFKDCADIVINDLSLIHQ
LPREEIQTFCYPSMIQKWSLDKYAMGGITTFTPYQFQHFSESLTASVDRI
YFAGEHTAEAHGWIDSTIKSGLRAARDVNRASEQ
3D structure
PDB1tdk Structures of L-amino acid oxidase in complexes with substrates and substrate analogue
ChainA
Resolution2.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) P92 H223 K326
Catalytic site (residue number reindexed from 1) P90 H221 K324
Enzyme Commision number 1.4.3.2: L-amino-acid oxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A V39 G40 G42 S44 L62 E63 A64 G70 R71 G87 P88 R90 Q260 V261 T294 G429 I430 E457 G464 W465 I466 T469 V37 G38 G40 S42 L60 E61 A62 G68 R69 G85 P86 R88 Q258 V259 T292 G427 I428 E455 G462 W463 I464 T467
BS02 LVG A R90 N208 H223 Y356 R88 N206 H221 Y354
BS03 LVG A R90 Y372 R88 Y370
Gene Ontology
Molecular Function
GO:0001716 L-amino-acid oxidase activity
GO:0016491 oxidoreductase activity
GO:0090729 toxin activity
Biological Process
GO:0006915 apoptotic process
GO:0009063 amino acid catabolic process
GO:0031640 killing of cells of another organism
GO:0035821 modulation of process of another organism
GO:0042742 defense response to bacterium
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1tdk, PDBe:1tdk, PDBj:1tdk
PDBsum1tdk
PubMed
UniProtQ6STF1|OXLA_GLOHA L-amino-acid oxidase

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