Structure of PDB 1ta0 Chain A

Receptor sequence
>1ta0A (length=181) Species: 9606 (Homo sapiens) [Search protein sequence]
MQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEIDGVVH
QVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRAR
LFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASW
FDNMSDTELHDLLPFFEQLSRVDDVYSVLRQ
3D structure
PDB1ta0 Structure and Mechanism of RNA Polymerase II CTD Phosphatases.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A X96 D98 N207 X21 D23 N132
Gene Ontology
Molecular Function
GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity
GO:0016791 phosphatase activity

View graph for
Molecular Function
External links
PDB RCSB:1ta0, PDBe:1ta0, PDBj:1ta0
PDBsum1ta0
PubMed15304220
UniProtQ9GZU7|CTDS1_HUMAN Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (Gene Name=CTDSP1)

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