Structure of PDB 1t9z Chain A

Receptor sequence
>1t9zA (length=181) Species: 9606 (Homo sapiens) [Search protein sequence]
MQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEIDGVVH
QVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADMLDKWGAFRAR
LFRESCVFHRGNYVKDLSRLGRDLRRVLIMDNSPASYVFHPDNAVPVASW
FDNMSDTELHDLLPFFEQLSRVDDVYSVLRQ
3D structure
PDB1t9z Structure and Mechanism of RNA Polymerase II CTD Phosphatases.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D96 D98 N207 D21 D23 N132
Gene Ontology
Molecular Function
GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity
GO:0016791 phosphatase activity

View graph for
Molecular Function
External links
PDB RCSB:1t9z, PDBe:1t9z, PDBj:1t9z
PDBsum1t9z
PubMed15304220
UniProtQ9GZU7|CTDS1_HUMAN Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (Gene Name=CTDSP1)

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