Structure of PDB 1t8s Chain A

Receptor sequence
>1t8sA (length=443) Species: 562 (Escherichia coli) [Search protein sequence]
LTPAQALDKLDALYEQSVVALRNAIGNYITSGELPDENARKQGLFVYPSL
TVTWDGSTTNPPKTRAFGRFTHAGSYTTTITRPTLFRSYLNEQLTLLYQD
YGAHISVQPSQHEIPYPYVILDRSMSAGLTRYFPTTFSPLSHFDARRVDF
SLARLRHYTGTPVEHFQPFVLFTNYTRYVDEFVRWGCSQILDPDSPYIAL
SCAGGNWITAETEAPEEAISDLAWKKHQMPAWHLITADGQGITLVNIGVG
PSNAKTICDHLAVLRPDVWLMIGHCGGLRESQAIGDYVLAHAYLRDDHVL
DAVLPPDIPIPSIAEVQRALYDATKLVSGRPGEEVKQRLRTGTVVTTDDR
NWELRYSASALRFNLSRAVAIDMESATIAAQGYRFRVPYGTLLCVSDKPL
HGEIKGAISEHLQIGIRAIDLLRAEGDRLHSRKLRTFNEPPFR
3D structure
PDB1t8s Structure of Escherichia coli AMP Nucleosidase Reveals Similarity to Nucleoside Phosphorylases
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.2.4: AMP nucleosidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FMP A N205 R381 W383 M404 E405 D428 K436 N174 R350 W352 M373 E374 D397 K405
BS02 FMP A H188 Y189 H157 Y158
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008714 AMP nucleosidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0009116 nucleoside metabolic process
GO:0044209 AMP salvage
GO:0046033 AMP metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1t8s, PDBe:1t8s, PDBj:1t8s
PDBsum1t8s
PubMed15296732
UniProtP0AE12|AMN_ECOLI AMP nucleosidase (Gene Name=amn)

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