Structure of PDB 1t88 Chain A

Receptor sequence
>1t88A (length=407) Species: 303 (Pseudomonas putida) [Search protein sequence]
NANLAPLPPHVPEHLVFDFDMYNPSNLSAGVQEAWAVLQESNVPDLVWTR
CNGGHWIATRGQLIREAYEDYRHFSSECPFIPREAGEAYDFIPTSMDPPE
QRQFRALANQVVGMPVVDKLENRIQELACSLIESLRPQGQCNFTEDYAEP
FPIRIFMLLAGLPEEDIPHLKYLTDQMTRPDGSMTFAEAKEALYDYLIPI
IEQRRQKPGTDAISIVANGQVNGRPITSDEAKRMCGLLLVGGLDTVVNFL
SFSMEFLAKSPEHRQELIERPERIPAACEELLRRFSLVADGRILTSDYEF
HGVQLKKGDQILLPQMLSGLDERENAAPMHVDFSRQKVSHTTFGHGSHLC
LGQHLARREIIVTLKEWLTRIPDFSIAPGAQIQHKSGIVSGVQALPLVWD
PATTKAV
3D structure
PDB1t88 Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding.
ChainA
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R186 G248 D251 T252 V253 C357 L358 G359 E366 V396
Catalytic site (residue number reindexed from 1) R179 G241 D244 T245 V246 C350 L351 G352 E359 V389
Enzyme Commision number 1.14.15.1: camphor 5-monooxygenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A P100 T101 R112 L244 G248 T252 V295 D297 R299 Q322 T349 F350 G351 H355 C357 G359 P93 T94 R105 L237 G241 T245 V288 D290 R292 Q315 T342 F343 G344 H348 C350 G352
BS02 CAM A Y96 L244 V247 Y89 L237 V240
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0018683 camphor 5-monooxygenase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0019383 (+)-camphor catabolic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:1t88, PDBe:1t88, PDBj:1t88
PDBsum1t88
PubMed15269210
UniProtP00183|CPXA_PSEPU Camphor 5-monooxygenase (Gene Name=camC)

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