Structure of PDB 1t4w Chain A

Receptor sequence
>1t4wA (length=196) Species: 6239 (Caenorhabditis elegans) [Search protein sequence]
EKWMEIDVLKQKVAKSSDMAFAISSEHEKYLWTKMGCLVPIQVKWKLDKR
HFNSNLSLRIRFVKYDKKENVEYAIRNPRSDVMKCRSHTEREQHFPFDSF
FYIRNSEHEFSYSAEKGSTFTLIMYPGAVQANFDIIFMCQEKCLDLDDRR
KTMCLAVFLDDENGNEILHAYIKQVRIVAYPRRDWKNFCEREDAKQ
3D structure
PDB1t4w Structural Differences in the DNA Binding Domains of Human p53 and Its C. elegans Ortholog Cep-1.
ChainA
Resolution2.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A C307 H310 C361 C365 C85 H88 C139 C143
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:1t4w, PDBe:1t4w, PDBj:1t4w
PDBsum1t4w
PubMed15242600
UniProtQ20646|CEP1_CAEEL Transcription factor cep-1 (Gene Name=cep-1)

[Back to BioLiP]