Structure of PDB 1syq Chain A

Receptor sequence
>1syqA (length=259) Species: 9606 (Homo sapiens) [Search protein sequence]
HMPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQA
AVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDP
YSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAE
VVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVK
ELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQ
LTSWDEDAW
3D structure
PDB1syq Structural basis for amplifying vinculin activation by talin
ChainA
Resolution2.42 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I12 Q19 M26 K35 P38 L40 V47 L54 V57 I115 F126 I13 Q20 M27 K36 P39 L41 V48 L55 V58 I116 F127
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0005198 structural molecule activity
GO:0051015 actin filament binding
Biological Process
GO:0007155 cell adhesion
Cellular Component
GO:0015629 actin cytoskeleton

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1syq, PDBe:1syq, PDBj:1syq
PDBsum1syq
PubMed15070891
UniProtP18206|VINC_HUMAN Vinculin (Gene Name=VCL)

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