Structure of PDB 1svu Chain A

Receptor sequence
>1svuA (length=307) Species: 726 (Haemophilus haemolyticus) [Search protein sequence]
MIEIKDKQLTGLRFIDLFAGLGGFRLALESCGAECVYSNEWDKYAQEVYE
MNFGEKPEGDITQVNEKTIPDHDILCAGFLFFDIARIVREKKPKVVFMEN
VKNFASHDNGNTLEVVKNTMNELDYSFHAKVLNALDYGIPQKRERIYMIC
FRNDLNIQNFQFPKPFELNTFVKDLLLPDSEVEHLVIDRKDLVMTNQEIE
QTTPKTVRLGIVGKGGWGERIYSTRGIAITLSAYGGGIFAKTGGYLVNGK
TRKLHPRECARVMGYPDSYKVHPSTSQAYKQFGNSVVINVLQYIAYNIGS
SLNFKPY
3D structure
PDB1svu Structure of the Q237W mutant of HhaI DNA methyltransferase: an insight into protein-protein interactions
ChainA
Resolution2.66 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E119 R163 R165
Catalytic site (residue number reindexed from 1) E99 R143 R145
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A F18 A19 G20 L21 E40 W41 D60 G78 S305 F18 A19 G20 L21 E40 W41 D60 G78 S285
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003886 DNA (cytosine-5-)-methyltransferase activity
GO:0008168 methyltransferase activity
Biological Process
GO:0009307 DNA restriction-modification system
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:1svu, PDBe:1svu, PDBj:1svu
PDBsum1svu
PubMed15195996
UniProtP05102|MTH1_HAEPH Type II methyltransferase M.HhaI (Gene Name=hhaIM)

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