Structure of PDB 1std Chain A

Receptor sequence
>1stdA (length=162) Species: 148305 (Pyricularia grisea) [Search protein sequence]
DEITFSDYLGLMTCVYEWADSYDSKDWDRLRKVIAPTLRIDYRSFLDKLW
EAMPAEEFVGMVSSKQVLGDPTLRTQHFIGGTRWEKVSEDEVIGYHQLRV
PHQRYKDTTMKEVTMKGHAHSANLHWYKKIDGVWKFAGLKPDIRWGEFDF
DRIFEDGRETFG
3D structure
PDB1std Crystal structure of scytalone dehydratase--a disease determinant of the rice pathogen, Magnaporthe grisea.
ChainA
Resolution2.9 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) Y30 D31 Y50 H85 H110
Catalytic site (residue number reindexed from 1) Y22 D23 Y42 H77 H102
Enzyme Commision number 4.2.1.94: scytalone dehydratase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BFS A Y50 L76 V108 N131 F158 F162 Y42 L68 V100 N123 F150 F154 PDBbind-CN: -logKd/Ki=10.33,Ki=47pM
BindingDB: Ki=47nM
Gene Ontology
Molecular Function
GO:0016829 lyase activity
GO:0030411 scytalone dehydratase activity
GO:0046872 metal ion binding
Biological Process
GO:0006582 melanin metabolic process
GO:0042438 melanin biosynthetic process
Cellular Component
GO:0005575 cellular_component
GO:0005768 endosome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1std, PDBe:1std, PDBj:1std
PDBsum1std
PubMed7866745
UniProtP56221|SCYD_PYRO7 Scytalone dehydratase (Gene Name=SDH1)

[Back to BioLiP]