Structure of PDB 1sps Chain A

Receptor sequence
>1spsA (length=103) Species: 11886 (Rous sarcoma virus) [Search protein sequence]
AEEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSDFDNA
KGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGLCHRLTNV
CPT
3D structure
PDB1sps Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A R12 R32 S34 E35 T36 K57 H58 Y59 K60 I71 R11 R31 S33 E34 T35 K56 H57 Y58 K59 I70
BS02 peptide A L64 D65 S66 L63 D64 S65
External links
PDB RCSB:1sps, PDBe:1sps, PDBj:1sps
PDBsum1sps
PubMed7680960
UniProtP00524|SRC_RSVSA Tyrosine-protein kinase transforming protein Src (Gene Name=V-SRC)

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