Structure of PDB 1sp4 Chain A

Receptor sequence
>1sp4A (length=48) Species: 9913 (Bos taurus) [Search protein sequence]
LPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNG
3D structure
PDB1sp4 Crystal structure of NS-134 in complex with bovine cathepsin B: a two-headed epoxysuccinyl inhibitor extends along the entire active-site cleft.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.1: cathepsin B.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EP2 A Q23 G27 C29 W30 Q23 G27 C29 W30
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1sp4, PDBe:1sp4, PDBj:1sp4
PDBsum1sp4
PubMed15084146
UniProtP07688|CATB_BOVIN Cathepsin B (Gene Name=CTSB)

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