Structure of PDB 1sk4 Chain A

Receptor sequence
>1sk4A (length=163) Species: 9606 (Homo sapiens) [Search protein sequence]
PNIIKRSAWEARETHCPKMNLPAKYVIIIHTAGTSCTVSTDCQTVVRNIQ
SFHMDTRNFCDIGYHFLVGQDGGVYEGVGWHIQGSHTYGFNDIALGIAFI
GYFVEKPPNAAALEAAQDLIQCAVVEGYLTPNYLLMGHSDVVNILSPGQA
LYNIISTWPHFKH
3D structure
PDB1sk4 Crystal structure of the C-terminal peptidoglycan-binding domain of human peptidoglycan recognition protein Ialpha
ChainA
Resolution1.65 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) Y242
Catalytic site (residue number reindexed from 1) Y64
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NA A S317 D318 V319 V320 I322 S324 Q327 S139 D140 V141 V142 I144 S146 Q149
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity
GO:0042834 peptidoglycan binding
Biological Process
GO:0009253 peptidoglycan catabolic process
GO:0045087 innate immune response

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1sk4, PDBe:1sk4, PDBj:1sk4
PDBsum1sk4
PubMed15140887
UniProtQ96LB9|PGRP3_HUMAN Peptidoglycan recognition protein 3 (Gene Name=PGLYRP3)

[Back to BioLiP]