Structure of PDB 1si3 Chain A

Receptor sequence
>1si3A (length=120) Species: 9606 (Homo sapiens) [Search protein sequence]
MAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQM
KRKYRVCNVTRRPASHQTFPLQVECTVAQYFKQKYNLQLKYPHLPCLQVG
QEQKHTYLPLEVCNIVAGQR
3D structure
PDB1si3 Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A H269 M273 R275 R278 F292 Y309 F310 Y314 K333 H334 T335 Y336 G347 Q348 H46 M50 R52 R55 F69 Y80 F81 Y85 K104 H105 T106 Y107 G118 Q119 PDBbind-CN: Kd=2.18nM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:1si3, PDBe:1si3, PDBj:1si3
PDBsum1si3
PubMed15152257
UniProtQ9UL18|AGO1_HUMAN Protein argonaute-1 (Gene Name=AGO1)

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