Structure of PDB 1sha Chain A

Receptor sequence
>1shaA (length=103) Species: 11886 (Rous sarcoma virus) [Search protein sequence]
AEEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSDFDNA
KGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGLCHRLTNV
CPT
3D structure
PDB1sha Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides.
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A R12 R32 S34 E35 T36 H58 Y59 K60 T72 S73 R11 R31 S33 E34 T35 H57 Y58 K59 T71 S72
External links
PDB RCSB:1sha, PDBe:1sha, PDBj:1sha
PDBsum1sha
PubMed1379696
UniProtP00524|SRC_RSVSA Tyrosine-protein kinase transforming protein Src (Gene Name=V-SRC)

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