Structure of PDB 1sgt Chain A

Receptor sequence
>1sgtA (length=223) Species: 1911 (Streptomyces griseus) [Search protein sequence]
VVGGTRAAQGEFPFMVRLSMGCGGALYAQDIVLTAAHCVSGSGNNTSITA
TGGVVDLQSGAAVKVRSTKVLQAPGYNGTGKDWALIKLAQPINQPTLKIA
TTTAYNQGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSAYGNELV
ANEEICAGYPDTGGVDTCQGDSGGPMFRKDNADEWIQVGIVSWGYGCARP
GYPGVYTEVSTFASAIASAARTL
3D structure
PDB1sgt Refined crystal structure of Streptomyces griseus trypsin at 1.7 A resolution.
ChainA
Resolution1.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H57 D102 Q192 G193 D194 S195 G196
Catalytic site (residue number reindexed from 1) H37 D82 Q169 G170 D171 S172 G173
Enzyme Commision number 3.4.21.4: trypsin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D165 A177A E180 E230 D138 A151 E154 E208
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1sgt, PDBe:1sgt, PDBj:1sgt
PDBsum1sgt
PubMed3135412
UniProtP00775|TRYP_STRGR Trypsin (Gene Name=sprT)

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