Structure of PDB 1sgf Chain A

Receptor sequence
>1sgfA (length=203) Species: 10090 (Mus musculus) [Search protein sequence]
NSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKEEPSDQ
HRLVSKAIPHPDFNMSLLPQPEDDYSNDLMLLRLSKPADITDVVKPITLP
TEEPKLGSTCLASICVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYT
CEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMA
NNP
3D structure
PDB1sgf Structure of mouse 7S NGF: a complex of nerve growth factor with four binding proteins.
ChainA
Resolution3.15 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H57 D102 E192 H193 D194 S195 G196
Catalytic site (residue number reindexed from 1) H32 D78 E152 H153 D154 S155 G156
Enzyme Commision number 3.4.21.35: tissue kallikrein.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A E75 H82 E45 H51
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1sgf, PDBe:1sgf, PDBj:1sgf
PDBsum1sgf
PubMed9351801
UniProtP00757|K1KB4_MOUSE Kallikrein 1-related peptidase-like b4 (Gene Name=Klk1b4)

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